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DNA technology now provides dual capabilities for data storage and computing

In a groundbreaking development, researchers from North Carolina State University and Johns Hopkins University have unveiled a revolutionary technology that utilizes DNA for data storage and computing functions. This innovative approach marks a significant advancement in the field of molecular computing, offering a comprehensive solution that combines the capabilities of traditional electronic devices with the unique properties of DNA.

The research, published in the journal Nature Nanotechnology, introduces a new technology called a „primordial DNA store and compute engine.“ Unlike previous DNA data storage and computing technologies, this new system is capable of performing a wide range of operations, including storing, retrieving, computing, erasing, and rewriting data. This breakthrough represents a major milestone in the quest to harness the power of DNA for advanced computing applications.

Albert Keung, the project leader and co-corresponding author of the paper, highlights the significance of this achievement. He explains that while conventional computing technologies rely on separate components for data storage and processing, the new DNA-based technology seamlessly integrates these functions into a single system. This integration opens up a world of possibilities for data storage and computing, bridging the gap between biological and electronic systems.

One of the key innovations that enable this technology is the development of soft polymer materials with unique morphologies. These materials, known as dendricolloids, feature a hierarchical structure of nanoscale fibers that provide a high surface area for DNA deposition. This allows for the efficient storage of large amounts of data in a compact space, making DNA an attractive option for long-term data storage.

The ability to distinguish DNA information from the nanofibers on which it is stored is a crucial aspect of the technology. This capability enables researchers to perform a wide range of functions, such as copying, erasing, rewriting, and computing specific data files. By depositing DNA on the dendricolloid material, the researchers can preserve the integrity of the data while carrying out these operations with precision and repeatability.

Kevin Lin, the first author of the paper, emphasizes the versatility of the new technology. He explains that the system allows for the direct copying of DNA information from the material’s surface without damaging the DNA. Additionally, targeted pieces of DNA can be erased and rewritten on the same surface, mimicking the functions of traditional electronic devices with remarkable efficiency.

Collaboration between researchers from different disciplines has been instrumental in the development of this technology. By combining expertise in polymer materials, microfluidics, nanopore sequencing, and algorithm development, the team has created a comprehensive solution that integrates various aspects of DNA data storage and computing.

The researchers have demonstrated the capabilities of the primordial DNA store and compute engine by solving simple sudoku and chess problems. The technology has shown promise for securely storing data for thousands of years without degradation, making it a viable option for long-term data storage applications. Moreover, the cost-effective and easy-to-fabricate nature of the dendricolloid host material makes it a practical solution for real-world implementation.

Overall, the development of this innovative DNA-based technology represents a significant step forward in the field of molecular computing. By combining the unique properties of DNA with advanced polymer materials and computational techniques, the researchers have created a versatile and efficient system that has the potential to revolutionize data storage and computing. This groundbreaking achievement paves the way for future advancements in molecular computing and inspires new possibilities for the integration of biological and electronic systems.

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